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The Influence of Corpus Luteum on IVF-PGT: Dr. Nathan Zhang from IVF USA Discusses IVF Success

2024-03-19 21:38:49,浏览量: 37次


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In the field of IVF-PGT and egg freezing, we often hear a term - corpus luteum. But do you understand its role and significance?


In IVF treatment, the corpus luteum plays an indispensable role. It is a tissue formed after ovulation, mainly composed of granulosa cells, and evolves under the action of luteinizing hormone (LH). This small tissue plays a crucial role in the IVF process, especially in regulating the state of the endometrium. The function of the corpus luteum is similar to preparing the soil before sowing seeds, providing an ideal environment for the implantation of fertilized eggs.


Every time after ovulation, the follicle forms the corpus luteum, also known as luteinization. At this time, the composition of granulosa cells will quickly recombine, and capillaries penetrate the follicular wall into the granular layer, forming the corpus luteum. The main task of this corpus luteum is to produce progesterone, which can promote the growth and repair of the endometrium, providing an ideal environment for the implantation of fertilized eggs. The corpus luteum is not permanent. If no conception occurs, it will naturally regress at the end of the menstrual cycle. But if conception occurs, the corpus luteum will continue to exist to ensure the success of conception.


Although we already have some understanding of the functions of the corpus luteum, the biochemical and endocrine reactions during its formation and regression process still require further research. The molecular mechanisms of granulosa cell migration and survival, as well as the effects of LH and hCG on granulosa cells, have not been fully elucidated. However, many studies have shown that the maturity and integrity of the corpus luteum are closely related to the strength of intercellular adhesion, which is crucial for the success of IVF.


Research by IVF experts has also found that inhibiting certain growth factors such as VEGF can almost completely inhibit the formation of the corpus luteum. These research results are consistent with our understanding of corpus luteum development and support the promoting role of certain growth factors in corpus luteum development.

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In summary, the corpus luteum plays an indispensable role in the IVF process.Understanding the formation and function of the corpus luteum is crucial for families in need of IVF treatment. Therefore, if you are considering IVF treatment, it is essential to pay attention to the role and impact of the corpus luteum. IVF USA has been committed to providing professional reproductive consultation and treatment services to patients. We have an expert team led by Dr. Nathan Zhang, a PhD from the University of Pennsylvania School of Medicine, who has rich experience and professional knowledge to provide you with the highest quality medical services. If you have any questions or need assistance regarding egg freezing, IVF, or corpus luteum, please feel free to contact our expert team. IVF USA currently provides services such as egg freezing and IVF in the United States, as well as IVF and egg freezing in Japan, Thailand, Mexico, Taiwan, Hong Kong, and other regions. We closely cooperate with top IVF doctors worldwide. We will provide you with personalized consultation and treatment plans to help you achieve your dreams and embark on a new journey of reproduction.


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