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In reproductive medicine, the importance of sperm quality for successful conception is often underestimated. Many people mistakenly believe that infertility issues mainly stem from the female partner, whereas the quality of the male's sperm is equally crucial. Through a real-life case, we can better understand the necessity of sperm fragmentation testing.
Mr. Zhang and his wife came to our reproductive center seeking assistance. His wife had been pregnant for two months but, unfortunately, experienced a miscarriage. At first, Mr. Zhang didn’t think he needed a sperm test and even questioned whether his sperm quality could be related to the miscarriage. However, the doctor’s suggestion led him to reconsider.
After a semen analysis, the results showed that Mr. Zhang’s sperm DNA fragmentation rate was as high as 55%, significantly above the normal level of 25%. This result shocked him and made him realize that the quality of male sperm should not be overlooked.
Sperm DNA fragmentation testing is a key component in assessing sperm quality. A high fragmentation rate may compromise the integrity of sperm's genetic material, thus affecting fertility. Studies have shown that the proportion of men with abnormal sperm DNA fragmentation is significantly higher among those with infertility issues compared to the general population.
For male patients preparing to undergo IVF-PGT, checking sperm DNA fragmentation rates is particularly important. Sperm quality directly impacts the success rate of IVF. In traditional IVF techniques, functionally normal sperm are necessary for effective fertilization. A high fragmentation rate may reduce the sperm’s fertilization ability, which in turn affects the success rate of fertilization.
It’s noteworthy that even if other semen parameters are normal, this doesn’t necessarily mean that sperm DNA fragmentation rates are also normal. Therefore, men who have experienced natural miscarriages, those with unexplained infertility, and those planning to undergo IVF should pay attention to sperm DNA fragmentation testing.
Besides lifestyle habits, sperm DNA fragmentation rates are also influenced by environmental factors. Long-term smoking, excessive alcohol consumption, and exposure to polluted environments may all lead to higher rates of sperm DNA fragmentation.
Therefore, men should take greater care of their reproductive health. If you or your partner are facing fertility challenges, consider undergoing sperm fragmentation testing to take timely, effective steps that may increase the chance of a successful conception. IVF USA currently offers egg freezing, IVF, and other reproductive assistance services in the USA. Our services have expanded to Japan, Thailand, Mexico, Taiwan, and Hong Kong, in collaboration with leading reproductive medicine experts worldwide. Dr. Nathan Zhang personally guides each case to help you fulfill your dreams. If you have any questions about sperm fragmentation testing or other reproductive health concerns, please feel free to contact us.
